Low HDL cholesterol linked to cognitive impairment
Low
serum concentrations of high-density lipoprotein (HDL) cholesterol are associated
with cognitive impairment and dementia. Total cholesterol, triglycerides, and
low-density lipoprotein and HDL cholesterol were measured in 561 85-year old individuals.
Mini-Mental State Examination scores were lower only in those individuals with
low HDL serum concentrations. These findings are of great clinical importance
because they suggest that increasing HDL cholesterol rather than lowering total
cholesterol might prevent the development of cognitive impairment and dementia,
the authors conclude